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Research Grants

The overall aim of OPERAM (OPtimising thERapy to prevent Avoidable hospital admissions in the Multimorbid elderly) is to optimise existing pharmacological and non-pharmacological therapy primarily in order to reduce avoidable hospital admissions among the elderly population aged ≥70 years with multimorbidity.
Specifically, the OPERAM consortium aims at:

  • Creating new evidence to prevent avoidable hospital admissions through optimising pharmacotherapy in the multimorbid elderly by performing a multi-centre cluster randomised clinical trial (RCT) to assess the impact of a structured medication review
  • Obtaining evidence-based data comparing pharmacological and non-pharmacological interventions to prevent common causes of avoidable hospital admissions in the elderly with multimorbidity, and rank these interventions according to their effectiveness and safety using network meta-analyses (NMA)
  • Identify the most cost-effective pharmacological and non-pharmacological interventions to prevent avoidable hospital admissions in the multimorbid elderly

COMPAR-EU is a multimethod, inter-disciplinary project that will contribute to bridging the gap between current knowledge and practice of self-management interventions. COMPAR-EU aims to identify, compare, and rank the most effective and cost-effective self-management interventions (SMIs) for adults in Europe living with one of the four high-priority chronic conditions: type 2 diabetes, obesity, chronic obstructive pulmonary disease, and heart failure. The project will provide support for policymakers, guideline developers and professionals to make informed decisions on the adoption of the most suitable self-management interventions through an IT platform, featuring decision-making tools adapted to the needs of a wide range of end users (including researchers, patients, and industry).

The Collaborative Outcomes study on Health and Functioning during Infection Times (COH-FIT) is a large international survey project for the entire population of countries affected by the coronavirus pandemic (COVID-19). The project involves almost 200 investigators in more than 35 countries and has been endorsed by multiple national and international professional organizations. The COH-FIT project aims to identify risk and protective factors that will inform prevention and intervention programs for the COVID-19 pandemic and should other pandemics occur in the future.

We are members of the guidelines subcommittee of the European Association for Endoscopic Surgery (EAES)


To advance MIS through improvement in quality and increased uptake of clinical practice guidelines in Europe and globally


To involve the surgical community, patient groups and healthcare authorities in the development of EAES guidelines
To standardize the methodology and improve the quality and reliability of EAES guidelines
To promote dissemination and use and clinical uptake of EAES guidelines
To become an information hub for all practitioners in MIS

Completed Projects We Participated

Get – Real

2013 – 2016

GetReal is a three-year project of the Innovative Medicines Initiative (IMI), a EU public-private consortium consisting of pharmaceutical companies, academia, HTA agencies and regulators (e.g., NICE, HAS, EMA and ZIN), patient organisations and SMEs. GetReal aims to show how robust new methods of RWE collection and synthesis could be adopted earlier in pharmaceutical R&D and the healthcare decision making process.


2010 – 2015

Integrating Multiple Meta-Analysis (IMMA) into health care praxis and research is a framework for establishing, disseminating and integrating the ‘second-generation’ meta-analysis toolkit.